Gene name:
Ier3(Gly96;Iex1);
Protein name:
Radiation-inducible immediate-early gene IEX-1;
Alternative:
Immediate early response 3 protein;Immediate early protein GLY96;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with the PPP2R5C-PP2A holoenzyme and ERK kinases; regulates ERK dephosphorylation.
Function:
May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme.
Subcellular Location:
Membrane
Single-pass type II membrane protein
Protein Attributes:
50:
MCHSRNHLHT | MTGLRAPSPA | PSTGPELRRG | SGPEIFTFDP | LPERAVVSTA |
100:
RLNTSRGHRK | RSRRVLYPRV | VRRQLPTEEP | NIAKRVLFLL | FAIIFCQILM |
150:
AEEGVSQPLA | PEDATSAVTP | EPISAPITAP | PVLEPLNLTS | ESSDYALDLK |

Vaild Sequence:
Related Databases
Uniprot:
FOR
ELISA Kit for Mouse Radiation-inducible immediate-early gene IEX-1
ELISA Kit for Mouse Radiation-inducible immediate-early gene IEX-1
CLIA Kit for Mouse Radiation-inducible immediate-early gene IEX-1
CLIA Kit for Mouse Radiation-inducible immediate-early gene IEX-1
Polyclonal Antibody for Mouse Radiation-inducible immediate-early gene IEX-1
Polyclonal Antibody for Mouse Radiation-inducible immediate-early gene IEX-1
Monoclonal Antibody for Mouse Radiation-inducible immediate-early gene IEX-1
Monoclonal Antibody for Mouse Radiation-inducible immediate-early gene IEX-1
Protein for Mouse Radiation-inducible immediate-early gene IEX-1
Protein for Mouse Radiation-inducible immediate-early gene IEX-1

R&D Technical Data
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Precision
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Recovery
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Linearity
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References
-
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain:
BALB/c.
-
2.
"Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis."
Hamidi T.
,
Algul H.
,
Cano C.E.
,
Sandi M.J.
,
Molejon M.I.
,
Riemann M.
,
Calvo E.L.
,
Lomberk G.
,
Dagorn J.C.
,
Weih F.
,
Urrutia R.
,
Schmid R.M.
,
Iovanna J.L.
J. Clin. Invest.122:2092-2103(2012)
[
PubMed]
[
Europe PMC]
[
Abstract]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: FUNCTION